Events concerning the Grand Theft Auto series in 2006.
- The first flashback parts of events in Manhunt 2 takes place.
- Jon Gravelli is charged with racketeering and is deemed unfit to stand trial due to being terminally ill, aged 83.
- Lenny Petrovic is arrested for assault, aged 24.
- William Hambrough is arrested for embezzlement and tax evasion, aged 36.
- Roman Bellic is arrested for public intoxication and disorderly conduct, aged 29.
- Real Badman is arrested for assault, aged 25.
- Alonso Gomez is arrested for possession of crack cocaine, aged 20.
- Ernesto Asaltacunas is arrested for possession of steroids, causing a doping scandal, aged 25.
- Frenchie Fox is arrested for indecent exposure, 28.
- Jeremy St. Ives is arrested for public lewdness, aged 30.
- Marnie Allen is arrested for petit larceny and prostitution, aged 19.
- Cloe Parker is arrested for possession of cocaine, aged 22.
- Kerry McIntosh is arrested for driving while intoxicated, aged 21.
- Samantha Muldoon is arrested for driving while intoxicated, aged 24.
- Chastity Quinn is arrested for arson, aged 18.
- Cherise McCormic is arrested for prostitution, aged 36.
- Heathcliff Waterstreet is arrested for burglary and illegal entry with intent, aged 31.
- Roy Zito is arrested for racketeering, aged 33.
- Frank Garone is arrested for racketeering, aged 29.
- Wu Lee is arrested for extortion, aged 46.
- Adam Dimayev is arrested for grand theft auto, aged 34.
- Goldberg, Ligner & Shyster filed an law suit against Rusty Brown's Ring Donuts and wins the case.
- Patrick becomes manager for the Doppler cinema on Vinewood Boulevard in Downtown Vinewood, Los Santos.
- Little Jacob is arrested for possession controlled substance: Marijuana, aged 24.
- Dardan Petrela is arrested for assault, aged 31.
- Jill Von Crastenburg is arrested for possession of controlled substance: Cocaine, aged 11.
- Mario Venturella is arrested for burglary: Illegal entry with criminal intent, aged 18.
- Harper died during a drug laboratory explosion, having already lost an ear.