At the drug deal, Niko Bellic, Playboy X and Johnny Klebitz are present. Charlie starts to act nervous which raises Johnny's suspicions. After the deal breaks up due to Johnny's suspicions, Charlie and his bodyguard open fire on the group. He is killed in the ensuing shootout.
During "Buyer's Market," Johnny cannot kill Charlie because after the cutscene, he is immediately killed by Niko.
A man working for the FIB named Agent Jones will later call Johnny, stating that Charlie was a colleague of his. He asks Johnny to give information to the FIB. Johnny, staying loyal to The Lost Brotherhood, refuses to do so.
He can be spared in GTA4 (not in TLAD) by simply only killing the NOOSE team. He and his friend are not required to be killed.