|Los Santos Freeway (HD Universe)|
Route 13 and Interstate 1 sign
|South end:||Strawberry Ave|
|North end:||Senora Freeway|
The highway begins from the south on Los Santos Blvd, at the intersection with the Del Perro Freeway in East Vinewood. It begins as a six lane urban freeway traveling through northeast, intersecting the Racetrack and Vinewood Bowl. It then begins to turn north while narrowing to a rural four-lane freeway at the Route 18 interchange, as it skirts along the western edge of the Tataviam Mountains. This part is co-signed with Route 13. At the intersection of the Palomino Freeway, I-1 loses its concurrency, and the freeway continues as the Senora Freeway .
- The Los Santos Freeway is the only highway to cross universes.
- The Los Santos Freeway is mentioned in Grand Theft Auto IV on the radio station Public Liberty Radio. One of the guests states that he had a chase scene on the Los Santos freeway.
- It is seen briefly in the GTA V Next-Gen Announcement Trailer, showing its dense traffic.