Mike drives Misty and two other female prostitutes to "high-rolling" clients, on orders from 8-Ball, in an attempt to find out information about the death of Vinnie. She later moves to Staunton Island and begins working for Yakuza co-leader Asuka Kasen, meeting Mike again when is sent by Asuka to deal with a pimp who had been stalking some of her girls.
By 2001, Misty has returned to living on Portland, and begun to work for Luigi Goterelli at his club, Luigi's Sex Club 7 in the Red Light District. She has also become the "regular girl" of prominent Leone Family member and mechanic Joey Leone, an associate of Goterelli's. She first meets Claude when he is sent to pick her up from Sweeney General Hospital and return her to the club. Claude and Misty meet once more when he drives her to Joey Leone's garage in Trenton. The two meet on one final occasion, when Claude is employed by Joey Leone to kill Mike Forelli, a prominent member of the Forelli Family.
- Misty is, in many ways similar to Grand Theft Auto IV's character Lola Del Rio. They are both prostitutes that are featured in nearly every promotional artwork for their respective games. The only difference is that Lola is an unseen character and was only used to promote the game, while Misty did appear in GTA III and GTA Advance.
- During the missions Luigi's Girls and Drive Misty For Me, the player can have Misty attack other non-playable characters by attacking them. Misty also makes statements such as "Leave me alone! Hey!".
- Misty is viewed as something of a mascot for Grand Theft Auto III due to her prominent role in the games promotion.
- A bar name Misty's appears in San Fierro in Grand Theft Auto: San Andreas, which may be a reference to Misty.
- During Luigi's mission Luigi's Girls, once you pick Misty up you can hear that she pronounces her name as "Mitsy."
- Misty is the only prostitute in the GTA series to appear in more than one game.
- She was originally wore a black miniskirt with red bra and a white jacket with gold high heels.
- Her name is based off the character from the Pokémon series
- Misty is the first known prosititue to be introduced in the GTA series.
- GTA III
- GTA Advance