The National Guard Depot is a National Guard military base located at Ocean Docks, Los Santos, San Andreas in Grand Theft Auto: San Andreas. The depot is featured in the mission Robbing Uncle Sam, in which Carl Johnson and Ryder attempt to break into the base and steal weapons for the Grove Street Families. Carl manages to unlock the gate and load a truck with the weapons using a Forklift. Then the duo escape the base in a Mule with the National Guard in pursuit.
This mission is the only instance in which military guards spawn at the base.