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The restaurant's name has the word Ecoli, which is a form of bacteria, where different strands do drastically different things. One strand is a cause for food poisoning, meaning that the name 'Ristorante Ecoli' is a comical name used by Rockstar Games, implying that the conditions are unsanitary within the restaurant.
A PSG-1 sniper appears on the balcony of the restaurant. Several soldiers also patrol its ruins.