The Sisyphus Theater is a 120-seat outdoor theater located in Vinewood Hills, Los Santos, west of the Vinewood Sign. It is based on the real life Greek Theatre in Los Angeles. Its upper deck has wooden tables and chairs and alfresco heaters.
- Sisyphus was a king in the Greek Mythology, and is referenced in the tale of Orpheus and Eurydice.
- Sorry Commode and Anguished Cornhole are set to perform as part of the project 'Rock Da House'.
- Hip hop artist Clay Jackson and Liberty City duo The Blue Brothers are also stated to be performing.
- Two women listening to music devices can be found talking to each other on the stage.