Does anyone know what his disease could be? I was thinking of cerebral palsy, but he doesn't have any kind of difficulties with speech, so I guess it can't be CP.
How did Lester not know Trevor was alive? He's a fucking drug and arms dealer using his real name. One of the 2 big plot holes I can't really get over. WikiJules (talk) 00:35, November 6, 2013 (UTC)WikiJules
As for the disease, during The Merryweather Heist (Freight), after Trevor says he called Lester and said that Lester was in the hospital, Michael mentions a wasting disease. So it's possible that he has something Muscle Atrophy or Osteoporosis.