The Wheelchair is a very slow vehicle in Grand Theft Auto: London 1969. Its speed is just as fast as a pedestrian walking and is definitely not the best getaway vehicle. It can be spotted near hospitals.
- There is an unusable wheelchair in Grand Theft Auto: San Andreas located in Fisher's Lagoon. It has the same model texture as some trash dumpsters that can be found around the State of San Andreas.
- Johnny Sindacco is confined to a wheelchair in Grand Theft Auto: San Andreas after a heart attack given by Carl Johnson. He later dies when falling out of his wheelchair due to another heart attack.
- Angus Martin is confined to a wheel chair in The Lost and Damned after Billy Grey caused an accident crippling him.
- In Grand Theft Auto V, Lester Crest uses a wheelchair due to his health condition. However, when he can't use it, he uses a cane.