- Madd Dogg: "Man! That fake-ass bitch Loc!"
- CJ: "Loc? But he's terrible."
- Madd Dogg: "Motherfucker! I knew there was something familiar 'bout those rhymes he was kickin'. They're from my rhyme book! That's my money! And those are my ho's! AND THAT'S MY VIDEO HE'S SHOOTIN' TODAY!"
- CJ: "OK. I say we make a cameo appearence."
- — Madd Dogg finds out that OG Loc stole his rhyme book
Cut Throat Business is the final mission for Madd Dogg in Grand Theft Auto: San Andreas given to protagonist Carl Johnson by him from his mansion in the Mulholland district of Los Santos, San Andreas.
Carl arrives at the mansion to find Madd Dogg back in the studio and ready to make his comeback. On TV, rival rapper OG Loc is holding a press conference and music video shoot. After listening carefully Madd Dogg realizes that the rhymes by OG Loc are actually from his rhymebook, which was stolen by Carl for OG Loc a long time ago. Carl and Madd Dogg both agree to drop-in unannounced and make a "cameo appearance" in the middle of Loc's video.
As the two arrive at the shoot, OG Loc is being interviewed. When he sees the two, he attempts to escape in a Vortex. Carl and Madd Dogg take the two other hovercrafts and give chase. In Verona Beach, Loc gets off his Vortex and switches to a go-kart. Carl and Madd Dogg again take the two other Go-Karts and continue chasing Loc through Los Santos. The chase comes to an end as Loc attempts to escape into the Blastin' Fools Records headquarters in Rodeo. Madd Dogg and Carl confront Loc, who initially denies the theft but then attempts to buy their silence. Jimmy Silverman, one of the executives of the record company, overhears the conversation and offers to sign Madd Dogg to the record label and sue Loc. Loc is sent to go get them all some lunch; his career is now finished. Madd Dogg takes back his rhymebook.
In order to complete the mission the player must:
- Take Madd Dogg to the video shoot
- OG Loc's making a run for it, don't let him get away
- Chase after OG Loc don't lose him
The player is rewarded with respect upon completing this mission. If the mission Grove 4 Life for Sweet Johnson has been done, the next mission Riot will be unlocked, triggering the endgame portion of GTA San Andreas. Also, there will now be Vortex and Kart spawn points (although the Vortex will always be in Valle Ocultado and the Kart will be possible to use and can be taken during the race Go-Go Karting as long as Back to School,Yay-Ka-Boom-Boom, Monster and Customs Fast Track are completed.)
- While you are chasing OG Loc, if you are far behind him, he'll drive slower; while being really close to him will make him drive faster, indicating that there is no way to get in front of him. This is known as rubberband AI, and is often seen throughout the Grand Theft Auto Series.
- There is an glitch in the PS2 version where Madd Dogg won't enter the BF Injection. Getting another vehicle will counteract this glitch as he will enter said vehicle and follow the player, and the mission will continue normally.
- The BF Injection you get in this mission has a unique colour red and black. You can save it by failing the mission, otherwise it's scripted not to disappear by the effect of a garage (which is essential to save a vehicle), even if it's destroyed.
- CJ and Madd Dogg shout to each other while driving to OG Loc as if to simulate the BF Injection's open cab, exposing the occupants to loud draft and engine noise. If the player uses another vehicle to get there, CJ and Madd Dogg will still shout to each other as if they are in a BF Injection. This is is because Rockstar only recorded this one version of the dialogue as they assumed the player would take the BF Injection over anything else due to its aesthetics and fast speed.
- The Vortex that Loc, you and Madd Dogg obtained is unique colour. You can save it by driving it into the Santa Maria Beach Safehouse garage, but it's difficult to get into the garage quick enough to catch up with Loc (using preferably a fast bike), thus continue the mission, due to the Vortex's poor handling.
- The walkway where Loc swaps vehicles is the same place where Madd Dogg's old manager is killed.
- The early part of this mission takes CJ into Flint County. Although Carl is free to continue roaming the state after this point, this is the final mission that will take Carl outside Los Santos proper.
- The groove music playing in the opening of the cutscene is exactly the same one used for the Max Heat TV commercial in Max Payne 2.
- It was also used in the beginning cutscene of Reuniting The Families.
- An easier way to chase OG Loc is with a bike (a car won't be able to drive up the narrow staircase near the end of the chase), if someone finds controlling the Kart difficult.
- It is possible to kill OG Loc through drive-bys from the side on his boat. (the bullets automatically hit his Vortex even if you're not directly positioned on his side) That will, however, cause the mission to fail.
- Madd Dogg will drown if the player drives the car into the water.
- Once the player loses to catch up to OG Loc, the player will respawn back at the last checkpoint if the player press yes to restart the mission. OG Loc will be on the dirt road and cannot move, thus the mission cannot be completed, unless you load up a save file or fail the mission and when the Pop-up appears the player press no. Happens on the IOS version of the game.
- The introductory cutscene has Madd Dogg recognize OG Loc's lyrics as being from his rhyme book. However, if someone listens very closely, the lines Loc raps are some of the lines from Madd Dogg's Rhymes and House Party.