D-Rail is a railroad company featured in Grand Theft Auto V. As of 2013, they operate trains in Los Santos. Their logo can be seen on containers hauled by trains.

The name of the company is an obvious pun on the word "derail".

Apparently its only the Wellcars who's owed by D-Rail and is hauled by Go Loco Railroad. It's unknown if D-Rail owes their own Locomotives.