In the original PS2 version of GTA Vice City, after achieving 100% completion, the Detonator won't disappear after using it because of the infinite ammo reward. A way to remedy this without dying or getting arrested, is to go through the metal detectors at Escobar International Airport or at the Leaf Links golf club. If Tommy has remote grenades, this will replace them with regular grenades. This has been fixed in later versions.
In GTA San Andreas, a bug occurs that if the player places a Satchel Charge in any place with the infinite ammo cheat and they use the detonator, it will never disappear, unless if they change the weapon in the projectile slot (e.g. grenades or molotovs).
In GTA San Andreas, if CJ uses the Detonator inside any casino (without place charges), it will attract the guards' attention, but the player won't gain police attention unless they attack the guards.
In the mission Wear Flowers in Your Hair in GTA San Andreas, if Zero is killed while he is sitting on the bench playing with the RC Raider, he will drop a Detonator. This was intentional, as the game developers wanted it to look like he was holding a remote control for the RC Raider that he was flying.