The agents wear the same uniform as the FBI, but without the hat and glasses. They also drive in different vehicles.
They appear in the mission The Exchange for the deal that was made by Ricardo Diaz. One of the agents appear in the mission The Mugshot Longshot to get Jerry Martinez into the witness protection program. And they were mentioned in the mission Turn On, Tune In, Bug Out when they bugged Lance's apartment in order to collect some evidence against the Vance brothers to have them arrested. They also sometimes monitor the handover of drugs during drug deals.
Grand Theft Auto: San Andreas
- Unnamed DEA agent (Deceased)
Grand Theft Auto: Vice City Stories
- The DEA was replaced by the Drug Observation Agency in the HD Universe.
- The DEA are based on the real life Drug Enforcement Agency.