East Holland Drug Gang is a small-time chapter of Afro-American Gangsters and drug dealers, based in East Holland. Clarence Little is the most successful member of a gang, having a lot of bodyguards and making money of pimping and drug dealing. One of his clients was Francis McReary, deputy police commissioner, and he really didn't want anybody to know about his dirty habits. Clarence started to blackmail Francis and he hired Niko Bellic to destroy the whole organization, Clarence Little personally and one of his lieutenants. The fate of gang after this is unknown.
- The East Holland Drug Gang share the same pedestrian skins as the North Holland Hustlers and the African Americans gangs.