Johnny Sindacco (-1992) is the Underboss of the Sindacco Family and son of the don of the Sindaccos (who is unnamed, but is implied an honorable and top ranking position in the organization, circa 1992; possibly Paulie Sindacco, who is the head in 1998). He was likely from Liberty City. His organization has turf in Liberty City and Las Venturas. When CJ first arrives in Las Venturas to Wu Zi Mu's newly opened casino, Johnny has been caught smashing up some of the slot machines. As Wu Zi Mu's men are about to "get rid of" Johnny, CJ intervenes and has Johnny tied to the hood of a car, stomach down, facing the front windshield. CJ then drives the Feltzer around the city dangerously in order to scare Johnny into telling him which family he's with.
Having been traumatized by the experience, Johnny spends time recovering in the hospital. At one point, some Forelli thugs hijack Johnny's ambulance in order to kill him. As CJ is helping Ken Rosenberg to prevent a war between the Leone, Forelli, and the Sindacco families, CJ highjacks the ambulance back from the Forelli thugs and drives Johnny back to safety.
However, when CJ later accompanies Ken to a meeting with Johnny, Johnny recognizes CJ, and having not fully recovered from his trauma, dies from a shock-induced heart attack, leading to a massive vengeful attack by Sindacco members.
- Johnny bears a strong resemblence to Christopher Moltisanti, Tony's nephew, from The Sopranos.
- Johnny is one of the few GTA characters who die of natural causes.
- GTA San Andreas