Lipurgex is a weight-loss drug seen advertised in Grand Theft Auto IV. It is available from its website and The drug is endorsed by Jill Von Crastenburg and Dr. Steven Von Singer. It is apparently a mix of caffeine, laxatives, diuretics, painkillers and amphetamines.

One of the commercials for the product in Grand Theft Auto IV reuses a monkey sound effect also used in the Pogo the Monkey radio commercial from Grand Theft Auto III.