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Loco Syndicate Drug Courier

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The Loco Syndicate Drug Courier is two sets of side missions in GTA San Andreas dealing with the Loco Syndicate's drug smuggling; Big Smoke's Cash and the Yay Courier. They are triggered by a phone call by Cesar on certain days of the week. These missions are unlocked by King in Exile and repeat until Smoke's Crack Factory is destroyed. They are not required for 100% Completion.


Big Smoke's Cash

On Mondays and Fridays, Cesar calls CJ to inform him that Big Smoke is sending money to the Loco Syndicate, with a courier leaving at 5am. If the mission is accepted, CJ must pursue a Patriot carrying the cash and ram it, causing boxes containing the payment to fall from the back so he can recover them. The mission ends if six boxes are picked up, the car gets too far away or arrives to Pier 69 in San Fierro. In the event of a mission failure, Carl gets to keep any money taken from the truck.

Yay Courier

At any time after midnight in Wednesdays & Saturdays, Vialpando may call Carl to notify him of a drugs shipment leaving San Fierro. The mission consists of pursuing a Sanchez-riding courier. A major difference with the first mission is that the target carries a backpack, which will drop the drugs as CJ shoots him, thereby reducing his pay.

As a result, the target must be killed as quickly as possible to minimize losses. Once the target is killed, Carl must recover his backpack. The end mission pay depends on the total percentage of drugs on it. The higher it is, the higher the pay.

If the player manages to steal it, a message that "YOU STOLE $X FROM THE COURIER"will appear on screen. If the player does not steal it, a message that "YOU STOLE $0 FROM THE COURIER" will appear on the screen.



Cesar: “The cash is leaving Los Santos again.”
CJ (yes): "OK, I'm on it."
CJ (no): “I’m gonna have to let this one slide man, I got too much shit on my plate."


You can try again every Monday and Friday


CJ: “Hey Cesar, the yay leavin' San Fierro, right?”
Cesar: “Right, but they’re using bikes CJ, they go cross country.”
CJ (yes): “OK, I’mma see what I can dig up.”
CJ (no): “Not right now, I gotta check into some shit.”


You can try again every Wednesday and Saturday


  • Up to 6 packets of $300 may be rammed off the Patriot during cash runs. Once $1800 has been collected the run is over for the day.
  • Up to $2000 can be stolen from the Yay Courier Bike each drug run.
  • A Rare BP, EP, FP Patriot may be obtained during the Cash runs. See walkthrough


  • The Patriot actually leaves from between CJ's and Sweet's houses though it comes from Smoke (presumably meant to be from Ryder who is listed as second in command on the Los Santos side of the operation).
  • Ironically, the pedestrians in the Patriot use the same model of the Grove Street members.
  • The bike "leaving from San Fierro" actually appears on a small bridge between Shady Creeks & Flint County whenever the phone call is received.
  • After the mission ends and stole the money you dropped, the Patriot will stop and stay here like there's nothing happening. If you try to jack the car, the door will be locked. Punch the car and the driver will close the door, trying to kill the player. Strangely, he's invisible and can't be killed with weapons. He can be killed when he got hit by a car however. The patriot is unique, as it is fire-proof, bullet-proof and damage-proof, but still can be destroyed when ramming it until it flips over


Big Smoke's Cash

  • The Patriot is bullet proof, fire proof, explosion proof, and the doors are always locked, so there's no real shortcut here.
  • Find a fast car that handles well. Haul up on the Patriot, slam into its rear, then slam on your brakes. The package often lands right on you if you stopped, plus you receive a lot less gunfire when you are only near it for a second, then backed way off again as it speeds away.
  • It starts in Grove street's cul-de-sac, so waiting there before 5am can give you a few good hits on pavement, before it starts off-roading.

Yay Courier

  • The courier starts dropping stuff once you shoot at him. The best approach is to run him over until he falls off the bike (try to smash him into another car or a wall). Then you can get a clean kill shot, and lose very little drugs/money.
  • The Rancher and Mesa make great vehicle for this mission as they can take off-road shortcuts to catch the bike quickly, and weigh enough to knock it over.

Video walkthrough

PC Version
GTA San Andreas Mission 41 Big Smoke's Cash04:35

GTA San Andreas Mission 41 Big Smoke's Cash

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