The Loco Syndicate Drug Courier, otherwise known as the Yay Courier, is one of two related side missions in GTA San Andreas dealing with the Loco Syndicate's drug smuggling operation, the other being Big Smoke's Cash. It's triggered by a phone call from Cesar every Wednesday and Saturday after CJ-and-friends flee Los Santos but before Smoke's Crack Factory is destroyed. It is not required for 100% Completion.
Cesar may call CJ to notify him of a drug shipment leaving San Fierro. The player can then accept or decline the mission without consequence. If accepted, the mission consists of pursuing an off-roading courier carrying a backpack full of drugs. Once the target is killed, the player must then recover his backpack. The end mission payout depends on the total percentage of drugs in it; the more drugs remaining, the higher the pay.
CJ will only receive the phone call for this mission if he is on foot. Otherwise, he will miss the call, and an onscreen message may be displayed at some point which reads "you received $0 from the courier, you can try again every Wednesday and Saturday".
- Up to $2000 can be stolen from the Yay Courier during each mission.
- The courier's backpack starts leaking drugs out after the player first damages him, which will affect the payout. Almost any motorcycle with a player-equipped Micro-SMG will work well enough, but for the cleanest of kills, it's best to first knock the courier off his bike, then quickly take him out before he gets back on it.
- To knock over the courier, the player will likely need a heavier vehicle; a Rancher or Mesa may be a good choice in order to chase him down through the country, while a fast car will allow the player to reach Los Santos ahead of him.
- The Yay Courier "leaving from San Fierro" can actually spawn anywhere on the outskirts of Los Santos when the phone call is received - between Angel Pine, Flint County, and Shady Creeks.
- The drug being carried by the Courier is likely Crack-Cocaine, as this is the primary drug that Big Smoke is pushing into Los Santos. Also, when damaged, the courier's backpack will leak a white powdery substance, consistent with the appearance of Cocaine.