Its slogan is: "We'll stretch to fit around your package". The company's depot is located next to Avery Carrington's construction site. The official uniform for the Spand Express workers are coveralls and their official truck is the Spand Express truck. In the mission Riot, Tommy Vercetti, on behalf of his lawyer Ken Rosenberg and real estate mogul Avery Carrington, changes into his coveralls at Rafael's, goes to the Spand Express depot and starts a riot among the striking Spand Express workers before destroying the Spand Express trucks that are parked in the Spand Express compound (presumably to drive them bankrupt), as Avery Carrington wanted the land that the Spand Express depot was occupying. After that mission, it is assumed Spand Express got disbanded as none of their workers and/or their trucks are seen again until the mission Phnom Penh '86, where a (presumed) Spand Express worker is seen jumping off a bridge to his death in the water below, possibly committing suicide as a result of losing his job. However, the player must be directing the camera behind the helicopter to see this.
- The name indicates it a parody of FedEx Express or UPS.
- In GTA San Andreas, in Blueberry, Red County, two warehouses next to the Xoomer warehouse you will see two signs saying Spand Express.