In Grand Theft Auto: Vice City, a wide array of weapons become available as the player completes more missions. There is a wide array of pistols, shotguns, and submachine guns, some of which can be purchased at Ammu-Nation. The game also features the most melee weapons in any GTA game until Grand Theft Auto 5, some of which can be bought at various hardware stores. Subsequently after the release of the original GTA Vice City for the PlayStation 2, Rockstar dropped the real names of the guns, probably due to trademark reasons likely being approached by Heckler & Koch, the maker of the MP5 and PSG1. Therefore some weapons on the list have two names, the first coming from the original PS2 version while the second coming from subsequent PS2 versions and the PC and Xbox versions. There are other physical differences to the guns between the original and subsequent versions, including the Ruger/Kruger is shortened and given a black skin, while the PSG1 is now standard with a mock silencer. Notice the weapon HUD is very unique and cannot be seen in any other games.

Slot 1: Unarmed
Brass Knuckles
Slot 2: Melee Weapons
Meat Cleaver
Golf Club GolfClub-GTAVC-icon
Nightstick Nightstick-GTAVC-icon
Baseball Bat BaseballBat-GTAVC-icon
Machete Machete-GTAVC-icon
Katana Katana-GTAVC-icon
Chainsaw Chainsaw-GTAVC-icon
Slot 3: Projectiles

Tear Gas
(PS2 version only)

Molotov Cocktail MolotovCocktail-GTAVC-icon
Grenades Grenade-GTAVC-icon
Remote Grenade Grenade-GTAVC-icon
Slot 4: Handguns
Colt .45/Pistol Colt45-GTAVC-icon
Colt Python/.357 Python-GTAVC-icon
Slot 5: Shotguns
Pump-Action Shotgun Shotgun-GTAVC-icon
Stubby Shotgun StubbyShotgun-GTAVC-icon
Combat Shotgun SPAS12-GTAVC-icon
Slot 6: Submachine Guns
Tec-9 TEC9-GTAVC-icon
Ingram Mac 10/Mac MAC-10-GTAVC-icon
Uzi 9mm/Uz-I MicroSMG-GTAVC-icon
Slot 7: Assault Rifles
Ruger/Kruger Ruger-GTAVC-icon
M4 M4-GTAVC-icon
Slot 8: Heavy Weapons
M-60 M60-GTAVC-icon
Flamethrower Flamethrower-GTAVC-icon
Rocket Launcher RocketLauncher-GTAVC-icon
Minigun Minigun-GTAVC-icon
Slot 9: Sniper Rifles
Sniper Rifle SniperRifle-GTAVC-icon
PSG-1/.308 Sniper PSG-1-GTAVC-icon
Slot 10: Others
Camera Camera-GTAVC-icon
Detonator Detonator-GTAVC-icon

The Remington 870 from GTA 3 was supposed to be featured but was removed for unknown reasons